import win32com

 from win32com.client import Dispatch,constants

 w = win32com.client.Dispatch('Word.Application')

 w.Visible = 0

 w.DisplayAlerts = 0

 doc = w.Documents.Open(FileName = r'C:\Users\jjw\Desktop\test\kewen\课文.rtf')

 par = doc.Range(doc.Content.Start,doc.Content.End)

 par.Font.Size = ""

 par1 = doc.Paragraphs(1).Range

 par2 = doc.Paragraphs(2).Range

 par1.Font.Size = ""

 par2.Font.Size = ""

 par1.ParagraphFormat.Alignment = 1

 par2.ParagraphFormat.Alignment = 1

 doc.Close()

 w.Quit