class Program

    {

        [STAThread]

        static void Main(string[] args)

        {

            //防止程序多次运行

            if (!OneInstance.IsFirst("MyTest"))

            {

                Console.WriteLine("警告:程序正在运行中! 请不要重复打开程序!可在右下角系统栏找到!");

                return;

            }

            Console.WriteLine("正在运行中");

            Console.ReadLine();

        }

    }

    public static class OneInstance

    {

        ///<summary>

        ///判断程序是否正在运行

        ///</summary>

        ///<param name="appId">程序名称</param>

        ///<returns>如果程序是第一次运行返回True,否则返回False</returns>

        public static bool IsFirst(string appId)

        {

            bool ret = false;

            if (OpenMutex(0x1F0001, , appId) == IntPtr.Zero)

            {

                CreateMutex(IntPtr.Zero, , appId);

                ret = true;

            }

            return ret;

        }

        [DllImport("Kernel32.dll", CharSet = CharSet.Auto)]

        private static extern IntPtr OpenMutex(

            uint dwDesiredAccess, // access

            int bInheritHandle,    // inheritance option

            string lpName          // object name

            );

        [DllImport("Kernel32.dll", CharSet = CharSet.Auto)]

        private static extern IntPtr CreateMutex(

            IntPtr lpMutexAttributes, // SD

            int bInitialOwner,                       // initial owner

            string lpName                            // object name

            );

    }