piece_size = 48

piece_size1 = 98464

with open("C:\\Users\\Administrator\\Desktop\\bins\\234.bin", "rb") as in_file, open("C:\\Users\\Administrator\\Desktop\\bins\\234_deal.bin", "ab+") as out_file:

    while True:

        piece = in_file.read(piece_size)

        piece1= in_file.read(piece_size1)

        if not piece:

            break

        if not piece1:

            break

        out_file.write(piece1)

    in_file.close()

    out_file.close()

#    f = open("C:\\Users\\Administrator\\Desktop\\bins\\OUT4.TXT", 'rb')

#    while True:

#        block = f.read(1024)

#        print(block)

#        if not block:

#            break

#    f.close()